Saturday, March 31, 2012

Healthy Weight Loss | Ididf Health & Fitness

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In the article by weight loss healthier than you have read the trend seems to focus on cutting fat and reducing your carbohydrates. What are all well and good, but there are many who seem lost in between. I think most of the time our health is not really focused on weight loss much more him. You can lose weight and still healthy. So in this article a healthy weight loss should be a balance. Just because someone can get a pound a go on a low fat, low carbohydrate diet does not mean they are healthy. I lost weight because this system and feel so weak at times and not very healthy.

What is the answer? I think the answer is that we have simply not getting the vitamins your body needs. Not because of insufficient weight loss is good, but we can not empty the nutrients we need if we are not complete. This is especially important as we age and our fertile years. Time has a way of saying that we need more than anything in our bodies that we do not receive. Personally, I have been taking vitamins for 7 years and I can say very little that I was in the doctor?s office. I can also testify that the good quality vitamin helps me not feel hungry. I think it?s because my body is getting what it needs each day. Personally, I have the product for 6 weeks and have more energy than I have in years. I eat well and drink two delicious shakes a day and I lost weight, but I?m healthier because of all the vitamins in the product. Life is short and a healthy helping us to live happier and that is not that what we all want. Start today and enjoy a healthier happier life.

This entry was posted in Weight Loss and tagged Healthy, Weight Loss. Bookmark the permalink.

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Real Estate Tax Update | Mountjoy Chilton Medley

Low Cost Financing Opportunity: Midwest Disaster Bonds

Some Midwestern hotel developers and medical office builders may now be able to obtain tax-exempt financing for certain 2012 projects.

In October 2008, Congress passed ?The Disaster Act?, which created a new category of federally tax-exempt bonds called Midwestern Disaster Area Bonds (?Disaster Bonds?). Disaster Bonds are designed to finance capital expenditures for business that suffered a loss caused by these disasters or are designated by the Governor as a trade or business that could have suffered a loss caused by these disasters. The window for issuing Disaster Bonds closes on December 31, 2012.

Disaster Bonds can be used to finance:

  • Acquisitions, constructions, reconstructions or renovations of non-residential real property (land, buildings and fixtures)
  • Multi-family rental properties for low and moderate income individuals
  • Repairing or reconstructing public utility property

It should be noted that The Disaster Act also limited the amount of Disaster Bonds that may be issued in the designated counties of the affected states. The following chart details this:

State Allocation Designated Counties
Illinois

$1.5?billion

Adams, Calhoun, Clark, Coles, Crawford, Cumberland, Douglas, Edgar, Hancock, Henderson, Jasper, Jersey, Lake, Lawrence, Mercer, Rock Island, Whiteside, and Winnebago

Indiana $3.0 billion

Adams, Bartholomew, Brown, Clay, Daviess, Dearborn, Decatur, Gibson, Grant, Greene, Hamilton, Hancock, Hendricks, Henry, Huntington, Jackson, Jefferson, Jennings, Johnson, Knox, Lawrence, Madison, Marion, Monroe, Morgan, Owen, Parke, Pike, Posey, Putnam, Randolph, Ripley, Rush, Shelby, Sullivan, Tippecanoe, Vermillion, Vigo, Washington, and Wayne

Missouri $1.4 billion

Adair, Andrew, Barry, Callaway, Cass, Chariton, Clark, Gentry, Greene, Harrison, Holt, Jasper, Johnson, Lewis, Lincoln, Linn, Livingston, Macon, Marion, Monroe, Newton, Nodaway, Pike, Putnam, Ralls, St. Charles, Stone, Taney, Vernon, and Webster

Source: http://www.mcmcpa.com/real-estate-tax-update/

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Friday, March 30, 2012

The Trademark Registration Checklist: 20 ... - Raw Business Law

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A quick Trademark Registration ?Boot-Camp? that aims to explain the legal and commercial benefits of trademark registration and what every business should know about how to protect the legal rights in their business name?.

1. Exclusivity: The One and Only

Trademark registration will confirm your legal ownership of the name or brand and enable you to stop others using your name for the same, or similar, goods or services. A successful trademark application will mean that you quickly become the only business that can use the name in your sector. This cannot be achieved by domain name registration or by company name registration. Any name you adopt should be legally available, satisfy the criteria for trademark registration and should be registered as a registered trademark without delay. Trademark registration will ensure that you have the exclusive right to use your particular name or brand in your product or service sector in the geographic market for which you have obtained registered rights.

2. Stay Safe: Avoid Infringement Claims

A successful trademark registration demonstrates conclusively that your name is deemed to be legally available in your market sector and does not belong to anyone else. It generally means that pre-registration searches showed your name to be free for use and registration and that no one else was able successfully to oppose your application. Once you have obtained a trademark registration, the risk that your use of the trademark will infringe the trademark rights of anyone else is vastly reduced. The converse is also true. If you steam ahead and adopt a trademark without checking if it is available, and protecting it by trademark registration, you are running a very high risk that you will sue for trademark infringement by the owner of the mark. This ultimately means court action against you to restrain your use of the brand, and award of damages, confiscation and destruction of infringing stock and heavy legal costs.

3. Protect Goodwill and Reputation

A strong and memorable brand that is protected by trademark registration is the surest legal foundation on which to build the reputation and goodwill of any business. A business that soldiers on without the benefit of a registered trademark is missing out on a huge commercial opportunity. Strong registered brands (Mercedes, Google, Amazon, iPad, The London Eye etc) quickly pass into the collective consciousness of the world consumer market and become synonymous with quality, consistency and reliability.

4. Get Noticed: Differentiate Your Business

The main purpose of a trademark is to denote the origin of the products or services to which the trademark is attached. The trademark becomes a badge of origin and quality. In short, the consumer knows where it came from and what to expect. So every business has an equal opportunity to adopt a distinctive brand that it alone owns and protecting it by trademark registration. This enables the business to differentiate itself from every other business in the same market sector. It makes no sense to adopt a name that is already in use, or is similar to an existing name, since this will not serve to differentiate your business from the competition. Your brand should be strong, memorable and unique and, for this reason, invented or quirky words tend to be best.

5. First is Best: Avoid Pre-emptive Registration

Once you have identified a legally available name that you want to adopt for your business you need to bang in a trademark application without any delay. If you do not do so, someone else may file an application before you and you will lose the opportunity to own the name exclusively. This may be because someone else has seen your name in print or, for example, at a trade-show, and thinks it is a good name that they would like to use. It may simply be an honest, concurrent application. Whether it is coincidental or intentional, the first application will usually take precedence. To avoid a pre-emptive application act fast and do not invest in any name until you know that you have successfully protected it by trademark registration.

6. Anti-Sabotage Measure: Competitors

If you fail to protect your name by trademark registration, you lay yourself wide open to attack by competitors you want to close you out of the market by filing an application to register your name and then alleging that your continued use of the mark constitutes trademark infringement. If a competitor gets a trademark registration for your name, or a very similar name, you may have to stop using your brand and could effectively lose your business overnight. It may be possible for you to seek a revocation of the competitor?s mark on the basis that you used it first or perhaps that the competitor is acting in bad faith but this is likely to cost you a very substantial amount in terms of legal costs and you may fall short on proof. Sometimes an oversea competitor will seek to register your trademark in national markets where you have not protected you name for the same products(eg by filing an EU or Community Trade Mark for all of the EU Member States) with the intention of preventing you from expanding into those markets or selling your products in those countries without rebranding your products for those markets.

7. Anti-Retaliation: Employees, Suppliers, Developers

Given that anyone can file an application to register a trademark if they have a genuine intention to use it, you can see that it is very easy for an aggrieved supplier or ex-employee, or anyone else who has a grudge against you, or your business, to retaliate by getting a trademark registration for your name if you yourself have neglected to protect it. This can cause you a major headache. It is quite common for developers or joint venture partners to make a pre-emptive, retaliatory application for trademark registration of the business name in order to give themselves a negotiating platform in the settlement of a wider, ongoing dispute. Prompt trademark registration in the first place closes off this avenue of attack and ensures that your business cannot be held hostage over the ownership of its own name.

8. ?Lock In? Brand Value

By protecting your business name by trademark registration you are effectively ?locking in? your brand value. If you think about it, if you develop your business under a brand that you have not take the trouble to check out and protect, you are taking the very real and inevitable risk that the name you are using is legally owned by someone else. In such a case, all of your hard work and advertising spend under that name is actually simply building up the goodwill and reputation of a business that is owned by someone else. When you are obliged to stop using the name you will lose any brand value that you may have acquired and will have to start again with a new name. Lock in the brand value of your business by trademark registration.

9. Defeat the ?Copy-Cats?

If you are successful, often competitors will try and copy your name and business model. They may, for instance, try and adopt a variant of your url. If you have protected your name by trademark registration, any copying of the domain name in this manner will probably amount to a trademark infringement and you will be able to stop them. Also, it is possible to protect, not just word marks, but also strap-lines, graphics, shapes and colours by trademark registration, so it is often possible to get a degree of exclusivity for the ?look-and-feel? of your business in this way, which also makes it much harder for competitors to copy your business idea effectively.

10. Assure Investors

Given the fundamental importance for any business of exclusive ownership of its brands and trademarks, potential investors often, quite rightly, require the business to demonstrate such ownership as a condition of making the investment. The most conclusive demonstration of ownership is a trademark registration certificate. Conversely, a conflict over name ownership is quite often a reason why investors do not proceed. Quite simply, they are not interested in buying into a legal dispute over the ownership of one of the main assets of the business.

11. Due Diligence: Satisfy Buyers

If you are planning to sell your business at any time, you will need to protect all of your names, marks and brands by trademark registration. Any prospective buyer will want to know that you have all of these rights under ownership and that there are no third parties using same name, which would obviously dilute the strength of the brand, or worse, actively seeking to prevent you from continuing to use your name. Since the value of the goodwill of your business is inextricably linked to the ownership of its trading name, failure to obtain a trademark registration can not only mean that you will not get the price you expect for your business, but, in difficult cases, your business may simply become unsaleable because of uncertainty or legal conflict over your right to use your current business or product name.

12. Support Expansion: Franchising, Licences, Agents

A strong brand protected by trademark registration is a sure footing on which to develop a business by way or franchise, licence or agency. A franchise is, in effect, nothing more than a glorified trademark licence and the very least that any franchisee will expect is the unfettered right to use the franchise name. The commercial benefit of being part of an umbrella brand is, after all, one of the main reasons that people invest in a franchise. A registered trademark can be licensed for a royalty. Any agency or distributorship network will want the comfort of knowing that you have the sole and exclusive legal right to use your product names and the only way this can be obtained conclusively is by way of trademark registration.

13. Company Registration: Control Company Name

Registration of your business name at Companies House, or any national company registration office, gives almost no name security or name ownership rights. In fact, at least in the United Kingdom, it simply means that no one can incorporate company under exactly the same name. Very similar names will often be accepted for registration. However, you protect your business name as a registered trademark, this will prevent any other company from incorporating your name into the name of their company the same products or services in which you trade. In the UK, if someone registers a company name that is the same as was similar to a trademark that you have protected by way of trademark registration, you can object to the Company Names Adjudicator and obliged the company to change its name to a different name.

14. Domains: Avoid Over-reliance on a URL

Whilst it is often difficult to register a descriptive URL as a registered trademark, there is no reason why a name that you have protected by web trademark registration cannot be incorporated into the domain name for your business. Anyone who tries to adopt the same or a similar domain name for similar products or services will then be infringing your registered trademark rights. Trademark registration therefore gives you a degree of control over your domain names and enables you to police similar URL registrations successfully.

15. First Mover Advantage: Protecting The ?Good Idea?

It is frequently the case that a good business idea cannot be protected legally in the sense that it is not possible to stop other businesses copying the idea as soon as it is launched. Provided the imitators do not infringe any copyright or patent rights they can usually replicate the idea. However, if you are first to market with your idea, you can secure first mover advantage by branding your idea with a strong and individual trademark that is protected by trademark registration. Often the idea itself becomes referred to in common parlance by the trademark itself and, whilst this is questionable from a strictly legal viewpoint, it is certainly a major commercial advantage and is a great help in securing and maintaining market share in the face of copycat competitors.

16. International Roll-Out: Secure Priority Dates

The filing of a trademark application secures a priority date for the future protection of the trademark. This means that if the business succeeds and it becomes necessary to protect the name by trademark registration more extensively in further jurisdictions, trademark applications can be filed in those jurisdictions within the applicable priority period (usually six months from first application) whilst still maintaining the benefit of the original filing date. This means that the protection afforded by any further trademark registration filed during the priority period will backdate to the date of the first trademark application and anyone that has used the trademark in the meanwhile will have been infringing the further trademark registration.

17. Cost-Proofing: Prevent Future Costs

Protecting the main business names by way of trademark registration is a relatively inexpensive process that effectively cost-proofs the business against the potentially very substantial costs of dealing with an alleged or actual trademark infringement. The costs that can be avoided in this way include not only your own legal costs, but liability to pay the legal costs of the aggrieved trademark owner, substantial compensation by way of damages, the loss of all infringing stock and, finally, the costs of carrying out a complete rebrand of the business (including all websites, facias, advertising and other printed material) and protecting the new brand by way of trademark registration.

18. Simplicity: Avoid Legal Complication

There is a satisfying simplicity to being able to hold a trademark registration certificate and wave it in the general direction of anyone who tries to use your name. That is usually sufficient to prevent infringement. In the absence of trademark registration is much harder and much more expensive to enforce common law trademark rights or sustain a case breach of copyright. The burden of proof involved in bringing such cases is substantial and the legal position in relation to her actions for passing off and copyright infringement is always complex. In the case of passing off it is necessary to prove substantial reputation, confusion in the marketplace and consequential financial loss. Legally, this places a huge burden on any business that can be avoided by trademark registration.

19. Logo Rights: Protect Graphics, Logos and Designs

It is possible to include in any trademark registration program not only the actual name of the business but also any logos, graphics or designs used in the business in relation to its products or services. In the absence of trademark protection, it is necessary to fall back on actions based on copyright and these are notoriously difficult to bring.

and so to bed??.

20. To Sleep at Night

The best reason for protecting your business by way of trademark registration!

For further information on trademarks and branding visit our Trademark Registration Web Resource

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Source: http://rawbusinesslaw.com/2012/03/29/the-trademark-registration-checklist-20-reasons-why-you-should-register-a-trademark-law-intellectual-property/

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Wednesday, March 28, 2012

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Sunday, March 25, 2012

Property Gymnasium Health And Fitness Tools Alternatives | wafful.org

[unable to retrieve full-text content]Property Gymnasium Health And Fitness Tools Alternatives. Years ago, BodyCraft home gym was very admired by the public. It offered something from numerous forms like free weights, physical exercise balls, rowing ...

Source: http://wafful.org/?p=466

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Mini DVD R | Computers and Technology

DVD-R or the digital versatile disk recorders can be ideally used for storing still pictures, digital audios, graphics, and data sharing. The mini DVD-R is the perfect option for sharing data, and comes in handy at business presentations and conventions. The compact disc size of 3 1/8 inches has a storing capacity of about 1.46 G B. This roughly translates to 30 minutes of audio or video recording.

These write-once discs are highly popular with consumers and have high compatibility with all major DVD-R brands of recorders, DVD Rom drives, DVD players and DVD-R camcorders. Downloads from the Internet can also be stored.

These mini DVD-Rs are easy to transport and are ideal for archiving. They have a shelf capacity ranging from 30 to 100 years and are a trusted way of storing valuable data. This feature gains all the more importance once you realize no matter how efficient the computer, there is always a risk of things going awry. If your system crashes, you will end up

losing all precious data and records. Therefore, it is always best to keep DVD-Rs handy because of their large storage capacity, their compactness, easy mobility and high shelf life. Using a high quality organic dye, the mini DVD-R ensures highly reliable audio and video quality and is readily available in the market.

If you are interested in buying a mini DVD-R, the best place to start searching is the web. You will come across innumerable companies offering attractive discounts and bargains.

Do remember to check out the quality of the DVD-Rs, especially in terms of their resistance to heat and ultra-violet rays. Most DVD-Rs have a high shelf life and come with a limited lifetime warranty.

Do a comparative study of a few websites and see what they are offering. This way you will be able to buy a mini DVD-R at a competitive rate.

DVDR provides detailed information about DVD Rs, DVDRs, DVD R discs, and more. DVDR is affiliated with Mini DV Tapes.

Source: http://www.mwstm.com/2012/03/24/Mini-DVD-R/

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Saturday, March 24, 2012

Meat-eating mammals lack sweet tooth, study finds

For all their sharp teeth, many meat-eating mammals lack a sweet tooth, a genetic analysis of a dozen species has shown.

The study, published this month in the journal Proceedings of the National Academy of Sciences, shows that carnivorous mammals whose diets don't feature much in the way of sugar may lose the ability to taste it at all.

Study coauthor Gary Beauchamp, director of the Monell Chemical Senses Center in Philadelphia, wasn't sure what he was expecting to find when he and his colleagues began looking at DNA samples of a dozen different species to study their taste receptor genes. But he knew that cats are indifferent to sweet carbohydrates and lack a working copy of a key taste receptor gene called Tas1r2.

"At the time, the feeling was that the cat was a very unusual anomaly among mammals in that it didn't respond to sweets," Beauchamp said. "But we wondered if the cat represented something that had happened many times."

Using DNA samples mostly provided by the San Diego Zoo, the team from Monell and the University of Zurich examined taste receptor genes in a dozen different mammals and found that seven species ? including sea lions, Asian otters and spotted hyenas ? lacked a properly functioning Tas1r2 receptor. All seven were meat- or fish-eaters.

The precise mutation in the Tas1r2 gene varied from species to species ? an indication that the loss of a sweet tooth wasn't something that occurred just once in the mammalian family tree, but happened independently at different points in time.

Sweet wasn't the only taste to disappear. Sea lions also appeared to lack functioning genes for detecting the savory tastes known to humans as umami. So did dolphins, which also lack working genes to detect different types of bitter substances. That was surprising to Beauchamp, he said, since bitterness is a useful warning of the presence of poison.

Altogether, the findings "illustrate the fact that the sensory world of animals is highly attuned to their dietary patterns," Beauchamp said.

The loss of major taste receptors in sea lions and dolphins makes sense given that these species often gulp their food without chewing, he added.

A similar pattern appears to hold for vegetarian mammals. Beauchamp pointed to research showing that bamboo-eating pandas have a well-developed palate for sweets, but they lack working umami receptors to detect savory, "meaty" foods.

Thomas Finger, a neurobiologist at the University of Colorado's Rocky Mountain Taste and Smell Center in Aurora, who was not involved in the research, said the study was "pretty impressive." Now he wonders whether the lack of working sweet genes is a sign that there's an evolutionary cost to maintaining an essentially useless taste receptor.

At the very least, he said, "it implies that as animals go to a more carnivorous diet, there's less and less advantage to it."

But Finger added one caveat. "They haven't tested the entire population" of these sweet-deprived species, he said. "If you looked in enough individuals you might find someone with the gene."

As for those cat owners who insist their feline loves chocolate or goes crazy for ice cream, Finger shrugged at humans' tendency to anthropomorphize their pets' tastes.

"Ice cream has a strong umami taste to it, so that's why your cat likes ice cream," he said. "It's the milk protein. We're very sensitive to sweets ? but the cat doesn't get it."

amina.khan@latimes.com

Source: http://feeds.latimes.com/~r/latimes/news/science/~3/RmCh4IJM03w/la-sci-mammal-taste-20120324,0,5848838.story

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Chamberlain has surgery after dislocating ankle

TAMPA, Fla. (AP) ? Yankees reliever Joba Chamberlain dislocated his right ankle while playing with his son at a local spot that had a trampoline, jeopardizing his immediate future after yet another odd misstep for New York's bullpen at spring training.

There was no timetable for Chamberlain's return. The team did not say whether the 26-year-old pitcher was using the trampoline equipment when he was injured Thursday.

The accident at a play area came two weeks after All-Star setup man David Robertson hurt himself moving boxes at home.

Yankees general manager Brian Cashman said Friday that Chamberlain had surgery and would be hospitalized at least a few days. The 6-foot-2, 240-pound righty was working his way back from elbow ligament replacement surgery and wasn't expected to return until June or July.

Asked Friday if this could threaten Chamberlain's career, Cashman said: "I'm not in position to say. Right now it's too early for that. He's in very good hands. He's a healer. He's a tough guy."

Bone broke through the skin during the dislocation. Chamberlain was scheduled for an MRI exam and CT scan Friday.

"My guess is he landed funny," Yankees manager Joe Girardi said.

Girardi said he spent about 30 minutes with Chamberlain at the hospital Friday morning that both of them were "a little emotional."

"I wanted to see how he was doing. You know it's crushing. I just told him, we're going to be here for him, we're going to get you through this and we're going to get you back on the mound. But you're going to go through some difficult times," Girardi said.

"You can only look forward. You've got to look forward. You can't look at 'what if?'" he said. "You can see the disappointment, there's no doubt that."

Earlier this month, Robertson stumbled on the stairs of his home in St. Petersburg while moving empty boxes for recycling. The Yankees' fears of a serious injury were abated when Robertson was diagnosed with a bone bruise.

And once it became clear Robertson's injury was minor, his teammates let him have it. Among those in the clubhouse weighing in with sarcastic cracks about carrying boxes was Chamberlain himself. Chamberlain often is like a big kid himself, joking with teammates and playing around.

But there was little humor coming out of the Yankees' camp Friday. The mood in the clubhouse was somber, and Cashman seemed shaken as he met with reporters. He even acknowledged at the end of the media session that he was rambling.

"He's facing a lot right now," Cashman said. "I can't tell you, really, anything more than something unfortunate happened. We're in the very early information side of this thing."

In January, Chamberlain agreed to a one-year contract for $1,675,000, up from $1.4 million last year. The deal was not guaranteed. Cashman said Friday it's not the right time to talk about Chamberlain's contract status.

As to whether this falls in the category of unacceptable off-the-field injuries, Girardi said: "I don't want to get into that now. What I want to talk about is getting him better and being there for this kid. He's going through a lot."

Cashman said Chamberlain's son was not hurt. The boy began kindergarten last year and Chamberlain often tweets about how proud he is of his son's hockey.

Chamberlain went 2-0 with a 2.83 ERA in 27 relief appearances last season before elbow surgery June 16. Now, another setback

"I feel extremely bad for him," Yankees captain Derek Jeter said. "He's worked hard to get his arm back in shape. A fluke accident. I feel extremely bad for him. He's got to be disappointed. I feel terrible for him."

Chamberlain was his usual playful self inside the Yankees' clubhouse Thursday and had a bullpen session set for Friday.

"From the baseball stuff, he was doing great," Cashman said. "I feel bad because I know how much he loves his game, and how much he was looking forward to coming back ahead of schedule. It's clearly derailed that, but what more does that mean, I don't know. A lot of things must be running through his mind."

Chamberlain has had an up-and-down career since joining the team in August 2007. He started out 2-0 with an 0.38 ERA in 19 relief appearances.

Chamberlain later inspired the "Joba Rules" that governed how much he would pitch, with the Yankees wary of overusing him while deciding whether he would be a starter, setup man or closer-in-waiting behind Mariano Rivera.

Source: http://news.yahoo.com/chamberlain-surgery-dislocating-ankle-150323262--mlb.html

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Friday, March 23, 2012

Introducing birth control in mosquitoes

Introducing birth control in mosquitoes [ Back to EurekAlert! ] Public release date: 22-Mar-2012
[ | E-mail | Share Share ]

Contact: Iqbal Pittalwala
iqbal@ucr.edu
951-827-6050
University of California - Riverside

Grant to UC Riverside's Alexander Raikhel can greatly help control population of disease-spreading mosquitoes

RIVERSIDE, Calif. Female mosquitoes require energy for their egg development, which they acquire from vertebrate blood. But by sucking on blood, they become vectors of numerous disease pathogens of human and domestic animals. If the mechanisms that govern their egg production are better understood, novel approaches to controlling the reproduction and population of mosquitoes can be devised.

Now a research team led by Alexander Raikhel, a distinguished professor of entomology at the University of California, Riverside, has received a five-year $2.8 million grant from the National Institutes of Health to study the molecular basis of hormonal regulation of mosquito reproduction.

The researchers will focus on deciphering the genes involved in mediating the action of hormones involved during egg production in mosquitoes specifically, Aedes aegypti, the mosquito that spreads dengue and yellow fever.

"What we are setting out to do is introduce birth control, based on hormones, in mosquitoes," said Raikhel, an expert in the molecular biology of mosquitoes and a member of the National Academy of Sciences. "Our task is to find a way to interrupt the host-seeking behavior of mosquitoes by manipulating their hormones and thus interrupting their egg development.

With egg development halted, the population of mosquitoes would eventually collapse."

Nearly 2.5 billion people are at risk for contracting dengue fever. Each year, there are 100 million cases of dengue in the world. Yellow fever results in 30,000 deaths per year; about 200,000 cases are reported each year.

Raikhel explained that a hormone unique to insects, called the "juvenile hormone," plays a key role in transforming a young female adult to a mature one that is capable of blood feeding, egg development, and thus spreading pathogens. The absence of this hormone in the body of the female mosquito impedes the growth of the mosquito to the adult stage. For the mosquito to reach the adult stage, levels of this hormone must first rise and then drop.

"This hormone is crucial for egg development," Raikhel said. "If we can figure out how its levels can be manipulated so that egg development is prevented, we can reduce the number of mosquitoes."

Each mosquito cell has a receptor for the juvenile hormone. The exact nature of this receptor, however, has eluded researchers for many years.

"In this project, we plan also to understand the structure and function of this receptor," Raikhel said. "One reason this receptor has been very difficult to study is that, unlike other receptors like it, it does not lie on the surface of the cell. Instead it lies inside the cell."

Raikhel's lab will attempt to block the action of the juvenile hormone's receptors.

"Several levels of interception can be designed in the lab so that no egg development in mosquitoes results," he said.

While his lab will focus in this project on only Aedes aegypti, the methods developed can be applied also to other disease-spreading mosquitoes.

###

Raikhel is recognized internationally for his significant contributions to insect science and vector biology. A leader in insect and mosquito reproduction and immunity, he is the author or coauthor of more than 160 research papers in international peer-reviewed scientific journals and books.

His research team includes the following researchers at UC Riverside: Tusar Saha, Zhen Zou, and Sang Woon Shin, all of whom work in Raikhel's lab; and Thomas Girke, an associate professor of bioinformatics.

The University of California, Riverside (www.ucr.edu) is a doctoral research university, a living laboratory for groundbreaking exploration of issues critical to Inland Southern California, the state and communities around the world. Reflecting California's diverse culture, UCR's enrollment has exceeded 20,500 students. The campus will open a medical school in 2013 and has reached the heart of the Coachella Valley by way of the UCR Palm Desert Center. The campus has an annual statewide economic impact of more than $1 billion. A broadcast studio with fiber cable to the AT&T Hollywood hub is available for live or taped interviews. UCR also has ISDN for radio interviews. To learn more, call (951) UCR-NEWS.


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Introducing birth control in mosquitoes [ Back to EurekAlert! ] Public release date: 22-Mar-2012
[ | E-mail | Share Share ]

Contact: Iqbal Pittalwala
iqbal@ucr.edu
951-827-6050
University of California - Riverside

Grant to UC Riverside's Alexander Raikhel can greatly help control population of disease-spreading mosquitoes

RIVERSIDE, Calif. Female mosquitoes require energy for their egg development, which they acquire from vertebrate blood. But by sucking on blood, they become vectors of numerous disease pathogens of human and domestic animals. If the mechanisms that govern their egg production are better understood, novel approaches to controlling the reproduction and population of mosquitoes can be devised.

Now a research team led by Alexander Raikhel, a distinguished professor of entomology at the University of California, Riverside, has received a five-year $2.8 million grant from the National Institutes of Health to study the molecular basis of hormonal regulation of mosquito reproduction.

The researchers will focus on deciphering the genes involved in mediating the action of hormones involved during egg production in mosquitoes specifically, Aedes aegypti, the mosquito that spreads dengue and yellow fever.

"What we are setting out to do is introduce birth control, based on hormones, in mosquitoes," said Raikhel, an expert in the molecular biology of mosquitoes and a member of the National Academy of Sciences. "Our task is to find a way to interrupt the host-seeking behavior of mosquitoes by manipulating their hormones and thus interrupting their egg development.

With egg development halted, the population of mosquitoes would eventually collapse."

Nearly 2.5 billion people are at risk for contracting dengue fever. Each year, there are 100 million cases of dengue in the world. Yellow fever results in 30,000 deaths per year; about 200,000 cases are reported each year.

Raikhel explained that a hormone unique to insects, called the "juvenile hormone," plays a key role in transforming a young female adult to a mature one that is capable of blood feeding, egg development, and thus spreading pathogens. The absence of this hormone in the body of the female mosquito impedes the growth of the mosquito to the adult stage. For the mosquito to reach the adult stage, levels of this hormone must first rise and then drop.

"This hormone is crucial for egg development," Raikhel said. "If we can figure out how its levels can be manipulated so that egg development is prevented, we can reduce the number of mosquitoes."

Each mosquito cell has a receptor for the juvenile hormone. The exact nature of this receptor, however, has eluded researchers for many years.

"In this project, we plan also to understand the structure and function of this receptor," Raikhel said. "One reason this receptor has been very difficult to study is that, unlike other receptors like it, it does not lie on the surface of the cell. Instead it lies inside the cell."

Raikhel's lab will attempt to block the action of the juvenile hormone's receptors.

"Several levels of interception can be designed in the lab so that no egg development in mosquitoes results," he said.

While his lab will focus in this project on only Aedes aegypti, the methods developed can be applied also to other disease-spreading mosquitoes.

###

Raikhel is recognized internationally for his significant contributions to insect science and vector biology. A leader in insect and mosquito reproduction and immunity, he is the author or coauthor of more than 160 research papers in international peer-reviewed scientific journals and books.

His research team includes the following researchers at UC Riverside: Tusar Saha, Zhen Zou, and Sang Woon Shin, all of whom work in Raikhel's lab; and Thomas Girke, an associate professor of bioinformatics.

The University of California, Riverside (www.ucr.edu) is a doctoral research university, a living laboratory for groundbreaking exploration of issues critical to Inland Southern California, the state and communities around the world. Reflecting California's diverse culture, UCR's enrollment has exceeded 20,500 students. The campus will open a medical school in 2013 and has reached the heart of the Coachella Valley by way of the UCR Palm Desert Center. The campus has an annual statewide economic impact of more than $1 billion. A broadcast studio with fiber cable to the AT&T Hollywood hub is available for live or taped interviews. UCR also has ISDN for radio interviews. To learn more, call (951) UCR-NEWS.


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Source: http://www.eurekalert.org/pub_releases/2012-03/uoc--ibc032212.php

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Video: iPad: Consumer Trap or Telecom Opportunity?

Some iPad users are finding out that their monthly data plans are being used up faster. Insight with Dennis Berman, Wall Street Journal.

Related Links:

Business & financial news headlines from msnbc.com

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Source: http://video.msnbc.msn.com/cnbc/46822057/

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Thursday, March 22, 2012

Dubai dreams again with new opera and art complex

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Source: http://news.yahoo.com/dubai-dreams-again-opera-art-complex-154513474.html

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Wednesday, March 21, 2012

Wall Street opens flat, Oracle gains

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Source: http://news.yahoo.com/stock-futures-signal-higher-open-oracle-eyed-092012204.html

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Florida real estate mortgage

Download PDF If you have a loan, your monthly payment of contributions, you find no source of funds, must you may to refinance to meet loan to your obligations. Refinancing the term refers only to the change of in debt provisions, so that you come across the rounds. Refinancing in Florida, at the best price, always a great feeling to find, if you can easily this do it is even better. If you find, what can your best deal, there no better way to look at things, rather than thoughts, tropical fruits and the weather, which discloses his it metaphor of the delicious fruit and attractive investment opportunities, are not simple word games when it comes to Florida mortgages. In contrast to other markets, to slower back on its feet after the Sun real estate market began to decline. This led to his location and

Florida mortgage company give not the pressure in a forced sale. They prefer to see a collection they are to turn the average amount of the mortgage. Understanding of the borrower in the same district of the crisis, like everyone else, the most important point in the future

A wise decision, and are getting better, more successful results. Looking after a buyer?s market to a new house or car, know your possibilities and the consequences of certain decisions, avoid you the financial accidents often occur in the future. Coursing its own direction from the outset on the right track to restart your home loans, refinance mortgage loan can give you additional flexibility, your payment. Florida refinance one of the benefits of tax cuts features such as the height of home acquisition debt limit. People may not know how their mortgages to work, therefore they were

Is a new family always on a large number of options on the market. For the first time at home find it perhaps too boring who is buyer it to go through it. But you narrow down your search, can you effectively shorten the time it takes to actually move your shopping cart

How to get rich has a number of books and experts, as you successfully build assets, and secure way to sell their secrets shared. Asset building is of great interest, especially for those that are willing to take the risk. But, of course, because it has often been said, a Florida mortgage is a financial leverage tool. If a mortgage loan, which is much more than the loan to take. If you verb in this word, you do things particularly that your assets you have the assets of the borrower Rao secured. If you

Source: http://www.zhan007.com/florida-real-estate-mortgage.html

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Tuesday, March 20, 2012

Search called off for missing climbers in Pakistan

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Source: http://news.yahoo.com/search-called-off-missing-climbers-pakistan-080250140.html

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The Phase Parents Go Through After Kid's ... - Education - EzineMark

As the time of a kid?s admission comes, it starts giving parents tight tensions. Many questions come and go in and from their minds. However, as per the government rules, the appropriate age of a kid?s admission in a school should be three years. If the parents feel that their kid is not prepared for school then they should make the kid appear for school willingness tests to agree on if a kid is apposite for the school admission. There are some documents that parents are required to submit during the kid?s admission.

There are other documents as well that they should present kid?s birth certificate, kid?s vaccination card and a transfer card or previous school statement if the kid has been to any other school. Education is very important aspect of our life which transforms a person to live an exotic life and more importantly a good social worker.

It teaches us all the attributes which is require leading proper lifestyle. Education makes one?s individuality an extraordinary one. It is something which provides us the power to move further and do something productive in near future.

Parents are required to undergo interview before their Childs admission just to ensure whether they are capable of sustaining school protocols.? Parents feel pressurize and their night go sleepless preparing for the school interview. It is very necessary that parents do a small research by communicating to the parents whose child is already admitted in a school. Such research will help them out in accepting the type of questions that are often asked to parents throughout the preschool interview. Every school has a definite schedule and they wait for the parents to get recognizable with this when they get their kid admitted.

Therefore, it is necessary for the school to carry out interview for both the parents and the children.

This is not only to protect the interests of the school but also to stay away from complications which can be arise in future connected to facilities and child development. Parents see many dreams while admitting their kids in school; they feel that it is the initial stair to provide the children with a good education so as to make them good human beings. The main purpose of the parents? discussion is to get a crystal clear depiction of the background of the kid, so that the teachers can get an enhanced understanding of the kid?s performance after the admission.

Parental participation in child edification is very necessary as they can only come to a decision what is apposite for the kid. There is basic reason for this involvement as they have managed their child lives since birth and resolve their trouble. Some parents have a belief that the child is not capable of handling complicated situations.? The responsibility of a parent does not end after the child?s education in fact they should become more conscious about their Childs performance. They should often visit the school and exchange conversation with the teachers so as to get a proper feedback of their children.? Parents? expectations also play a great role in influencing the child to do best.

Source: http://education.ezinemark.com/the-phase-parents-go-through-after-kids-admission-in-school-7d34b451a0ae.html

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Monday, March 19, 2012

93% Mission: Impossible Ghost Protocol

All Critics (194) | Top Critics (37) | Fresh (179) | Rotten (13)

Brad Bird passe his audition for a career as a live-action director. And "Ghost Protocol" more than makes its bones as an argument for why Tom Cruise should continue in this role as long as his knees, and his nerves, hold up.

Brad Bird passes his audition for a career as a live-action director. And "Ghost Protocol" more than makes its bones as an argument for why Tom Cruise should continue in this role as long as his knees, and his nerves, hold up.

"Mission: Impossible-Ghost Protocol" is sheer hurtling mechanism-and it's great silly fun.

As usual with the series, the movie combines a plot line a toddler could understand with gadgets that would baffle an engineering Ph.D.

I'm thinking it, so I might as well say it: Mission: Impossible - Ghost Protocol is no Fast Five.

...it's pretty much state-of-the-art.

Brad Bird's Mission made me feel like a kid again.

... a good-size barrel of fun.

still does not have the hang of what made the TV show so good.

Cruises on the WOW! factor.

Snagging Oscar-winning animation director Brad Bird to fill the director's chair proves to be an inspired choice--and, upon thought, a bit of a no-brainer.

The screenplay doesn't rely too much on gimmicks to advance the plot. Instead, the plot is also character-driven to an extent. There are interesting dynamics going on in the Mission Impossible team.

Director Brad Bird juices and gooses the whole affair with edge and excitement, new energy, humor and heartbeat, and a terrific feel for big, bold, audaciously daring sequences that beg for the biggest screen available.

Great stunts and not a dull moment,

Mission: Impossible -- Ghost Protocol could very well be the series' best installment.

It has a few very good ideas, and then, the rest of it is totally lackluster.

Watching Tom leap from a hospital window on to a passing truck, I couldn't help but worry: Tom, those knees won't last forever.

Succeeds in dishing up exactly what you would expect: State of the arts stunts, non-stop action, and a series of clearly laid-out heists and chases that go awry in all kinds of creative ways.

Bird manages the escalations from the preposterous through the more preposterous to the most preposterous with skill and wit...

...great cinematic entertainment.

Better than the tower climb is the scene in which Hunt infiltrates the Kremlin with, essentially, a high-tech magic trick; the playfulness of the effect demonstrates the usefulness of Bird's background in the astonish-the-audience culture of animation.

More Critic Reviews

Source: http://www.rottentomatoes.com/m/mission_impossible_ghost_protocol/

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March Madness - Does it Affect Work?

If surveys are right, American productivity is taking a big hit down this week, thanks to March Madness ? the NCAA Men's Division I Basketball Championship. Every Americans might have their own?March Madness Bracket?now.

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U.S.

businesses owners and managers are getting their selves ready as workers follow the tournament on their computers, iPods, and iPads. It's been estimated that 2.5 million workers will access online coverage of the NCAA basketball tournament, and those fans will spend an average of one and a half hours a day watching games and highlights. In a recent survey, more than 40 percent of IT professionals said that the spike in internet use has affected their office computer operations in recent years, in some cases causing their systems to grind to a halt.

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This year, estimates of lost productivity range from $175 million to $1 billion. But what do we really know about the connection between March Madness and worker productivity? Through my research, I came up with clear evidence of the NCAA tournament's effect on patterns of work. Whether it's a serious problem is another question.

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My research suggests that the tournament has a profound and widespread impact on patterns of work. The clearest effect was a significant drop in articles viewed during the week following Selection Sunday. In each of the three years I observed, the daily number of articles that users looked at this week dropped about 6 percent. This decline started on Monday and lasted the entire week. This 6% drop affected everybody. It didn't matter if the library in question had a team in the tournament or even if they had a Division I basketball team at all. But I wouldn't necessarily say these effects ? as clear and consistent as they were ? represent declines in productivity.

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So a true test of whether or not the tournament causes any real decline in work must focus on how fans respond to unanticipated outcomes. Tracing fan behavior in these cases is akin to a natural experiment, because the outcome of any game is more or less a random occurrence. For universities whose team won unexpectedly, it was party time: work declined 19% the following day, but for that day only. But when a team lost one of these games, there was no effect.

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Big-time college sports leaves a giant footprint, and the influence of March Madness on patterns of work is just one example. But American productivity probably isn't affected too much, no more than it is by, say, Thanksgiving. In conclusion, people have fun during March Madness. They take out their?March Madness Bracket?for some time and watch the NCAA coverage but most of them find a way to get their work done so there?s no need to worry about. Let?s just enjoy this great season in sports and let?s all get hook up in March madness craze!

Source: http://leisure.ezinemark.com/march-madness-does-it-affect-work-7d34c685b2e2.html

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Sunday, March 18, 2012

Document and Business Processing Outsourcing solutions to ...

The secret to your organisation?s success: leveraging your corporate information to have greater insight about your customers and to make timely and accurate decisions. Swiss Post Solutions? services and solutions optimise how you manage your inbound and outbound document and information flows. Swiss Post Solutions? provides its clients with the ability to cost-effectively onboard and distribute physical and electronic documents throughout the organisation, allowing our clients to: ? Simultaneously improve productivity and reduce operational costs ? Take an enterprise-wide approach to automating business processes ? Enable improved decision making and customer satisfaction by accelerating business transactions ? Reduce the risk of non-compliance by achieving legislative and regulatory requirements Regardless of document type, physical or electronic medium, format, language or geographic location, Swiss Post Solutions offers an end-to-end solution from document creation to content management, production, distribution and business intelligence. Our services include: ? Mailroom and Office Services Facilities Outsourcing ? Digital Mailroom ? Document Processing; including invoice processing, claims processing, application/order form processing ? Business Process Outsourcing; including Customer Loyalty Management and e-Commerce Channel Management Visit www.swisspostsolutions.com to learn more about our solutions.

Source: http://electronic-dms.info/document-and-business-processing-outsourcing-solutions-to-leverage-corporate-information/

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Saturday, March 17, 2012

Common Personal Injuries that May Warrant Legal Action - Malman ...

Last updated 15 hours ago

A personal injury case refers to a legal dispute that occurs when one person suffers harm due to an accident or injury. In some cases, a personal injury case may be the result of negligence on the part of another individual or corporation. In order to gain compensation for their injuries, many individuals choose to consult with a personal injury lawyer.

Automobile Accidents

There are a number of personal injuries that may warrant legal action, including car accidents, trucking accidents, and motorcycle accidents. Individuals who are injured in an automobile accident may be eligible for compensation in the event that the accident was due to the negligent or dangerous actions of another or vehicle malfunctions. However, injured parties often require the assistance of an injury attorney in order to gather the evidence needed to prove that the injury was the result of a negligent action.

Medical Malpractice

Individuals who are the victims of medical malpractice can also take legal action to gain compensation for their injuries. Medical malpractice may include but is not limited to misdiagnosis, delayed emergency treatment, inaccurate administration of medications, and the failure to screen for allergic reactions. Medical malpractice lawsuits are extremely complex and require thorough preparation and investigation?increasing the need for an experienced personal injury attorney.

Slips and Falls

Another common personal injury that may warrant legal action is a slip and fall injury. In order for individuals to have a valid case, they will need to demonstrate that the slip and fall injury was not the cause of their own actions. For example, an individual may have a claim if they slipped and fell in a grocery store due to the negligence of the owner to clean up a spill or place a ?wet floor? sign. Individuals may also have a case if they fell due to insufficient lighting at an apartment, uneven cracks on a sidewalk, or broken steps in a stairwell.

At Malman Law, our personal injury attorneys are focused on providing our clients with incredible customer service and legal representation.? Learn more about personal injury law by contacting our Chicago office at (312) 985-9273.

Source: http://www.malmaninjurylawchicago.com/397496/2012/03/16/common-personal-injuries-that-may-warrant-legal-action-.html

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Make Your Home Improvement Projects Easier With These Quick ...

So, you?ve made it. You?re ready to get into home improvement right? Well, now is the perfect time. You probably have a lot of questions on how to start and what to do, but don?t worry, this article has you covered. Listed below are some tips that will help you get started with your home improvement plans.

Free up some cabinet space in your kitchen by using a metal desk organizer to store cutting boards, jelly roll pans and cookie sheets. This will not only give you the much needed cabinet space, but keep you from having to open every single drawer in your kitchen to find one item you could use.

Don?t be afraid to use bright colors in the decor of your home. Paint a wall pink or red if you want to. It?s only paint, you can always re-paint it later. The most important thing is letting your own personality shine through in the style of your home.

When considering doing some home improvements, think about the time that the new appliances you are purchasing will last. A new refrigerator should last a minimum of twenty years, while a washer and dryer only has a life span of a little more than half that. So choose your appliance wisely when doing any remodeling project.

When it comes to home improvement, it is important to realize that the more customized your have, the less likely it will be appreciated by your future buyers. If you are concerned about the resale value of your house, it is important to appeal to the general public as opposed to your own tastes.

Home improvement can be done quickly and easily and many of the projects can be done by you and your family and friends. Painting your home either on the interior or exterior is one great option to change the entire look as well as give a nice update to your house.

To improve the value of your home, you should think about remodeling it. A home that looks new can be sold for more. Adding new rooms or an outside patio can increase its value. Consider remodeling as a form of investment and make sure you know what most people want, before you start.

Electrical Projects

Some home improvement project are easier than others. Be realistic about your level of skill before you tackle any home improvement project. Painting and wall paneling are good projects for beginners and can quickly transform a room. Plumbing and electrical projects are best left to qualified professionals unless you have experience in these areas.

As you may now be aware, home improvement projects are not as daunting as they may seem at first. By proceeding in a project, you are not only improving your home, you are gaining experience to use in future projects. By following the tips from this article, you will help equip yourself with the knowledge necessary to take on your next project.

To get additional useful information, please go to electrical projects; optionally you should also check out here.

Source: http://treasuredarticles.com/home-improvement/appliances/make-your-home-improvement-projects-easier-with-these-quick-solutions

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